Wayne T. McCormack, Ph.D.
Associate Professor
Department of Pathology, Immunology and Laboratory Medicine
University of Florida College of Medicine
Gainesville, Florida

Publications


PEER REVIEWED PUBLICATIONS
  1. McCormack, W.T. & K.H. Roux.  1982.  Monoclonal antibodies specific for the b5 allotype of rabbit kappa light chains.  Hybridoma 2:97-107.  abstract
  2. Roux, K.H., W.T. McCormack & P. Dhanarajan.  1985.  A reevaluation of rabbit anti-allotype antibody for the presence of cross-reactive idiotypes.  I.  A species-specific idiotype on rabbit anti-a1 antibody is recognized by guinea pig anti-IdX antibody.  J. Immunol. 135:1961-1966.  abstract
  3. Roux, K.H., W.T. McCormack & P. Dhanarajan.  1985.  A reevaluation of rabbit anti-allotype antibody for the presence of cross-reactive idiotypes.  II.  Expression of rabbit a1-like images on goat antibody after immunization with anti-a1 antibody.  J. Immunol. 135:1967-1974.  abstract
  4. McCormack, W.T., S.M. Laster, W.F. Marzluff & K.H. Roux.  1985.  Dynamic gene interactions in the evolution of rabbit VH genes: a four codon duplication and block homologies provide evidence for intergenic exchange. Nucleic Acids Res. 13:7041-7054.  abstract
  5. McCormack, W.T., P. Dhanarajan & Roux, K.H.  1988.  Comparison of latent and nominal rabbit Ig VHa1 allotype cDNA sequences.  J. Immunol. 141:2063-2071.  abstract
  6. McCormack, W.T., L.W. Tjoelker, L.M. Carlson, B. Petryniak, C.F. Barth, E.H. Humphries & C.B. Thompson.  1989.  Chicken IgL gene rearrangement involves deletion of a circular episome and addition of single nonrandom nucleotides to both coding ends.  Cell 56:785-791.  abstract
  7. McCormack, W.T., L.W. Tjoelker, C.F. Barth, L.M. Carlson, B. Petryniak, E.H. Humphries & C.B. Thompson.  1989. Selection for B cells with productive IgL gene rearrangements occurs in the bursa of Fabricius during chicken embryonic development.  Genes Dev. 3:838-847.  abstract
  8. McCormack, W.T., L.M. Carlson, L.W. Tjoelker & C.B. Thompson.  1989.  Evolutionary comparison of the avian IgL locus: Combinatorial diversity plays a role in the generation of the antibody repertoire in some avian species.  Internatl. Immunol. 1:332-341.  abstract
  9. Petryniak, B., L.M. Staudt, C.E. Postema, W.T. McCormack & C.B. Thompson.  1990.  Characterization of chicken octamer-binding proteins demonstrates that POU-containing homeotic transcription factors have been highly conserved during vertebrate evolution.  Proc. Natl. Acad. Sci. USA 87: 1099-1103.  abstract
  10. Carlson, L.M., W.T. McCormack, C.E. Postema, C.F. Barth, E.H. Humphries & C.B. Thompson.  1990.  Templated insertions in the rearranged chicken IgL V gene segment arise by intrachromosomal gene conversion.  Genes Dev. 4:536-547.  abstract
  11. McCormack, W.T. & C.B. Thompson.  1990.  Chicken IgL variable region gene conversions display pseudogene donor preference and 5' to 3' polarity.  Genes Dev. 4:548-558.  abstract
  12. Tjoelker, L.W., L.M. Carlson, K. Lee, J. Lahti, W.T. McCormack, J.M. Leiden, C.H. Chen, M.D. Cooper & C.B. Thompson.  1990.  Evolutionary conservation of antigen recognition: The chicken T cell receptor b chain.  Proc. Natl. Acad. Sci. USA 87: 7856-7860.  abstract
  13. Roux, K.H., P. Dhanarajan, V. Gottschalk, W.T. McCormack & R. Renshaw.  1991.  Latent a1 VH germline genes in an a2a2 rabbit:  Evidence for gene conversion at both the germline and somatic levels.  J. Immunol. 146:2027-2036.  abstract
  14. Carlson, L.M., M.A. Oettinger, D.C. Schatz, E.L. Masteller, E.A. Hurley, W.T. McCormack, D. Baltimore & C.B. Thompson.  1991.  Selective expression of RAG-2 in chicken B cells undergoing immunoglobulin gene conversion.  Cell 64:201-208.  abstract
  15. Turka, L.A., D.G. Schatz, M.A. Oettinger, J.J.M. Chun, C. Gorka, K. Lee, W.T. McCormack & C.B. Thompson.  1991.  Thymocyte expression of RAG-1 and RAG-2: Termination by T cell receptor cross-linking.  Science 253:778-781.  abstract
  16. McCormack, W.T., L.W. Tjoelker, G. Stella, C.E. Postema & C.B. Thompson.  1991.  Chicken T-cell receptor b-chain diversity:  An evolutionarily conserved Db-encoded glycine turn within the hypervariable CDR3 domain.  Proc. Natl. Acad. Sci. USA 88:7699-7703.  abstract
  17. McCormack, W.T., E.A. Hurley & C.B. Thompson.  1993.  Germline maintenance of the pseudogene donor pool for somatic immunoglobulin gene conversion in chickens.  Mol. Cell. Biol. 13:821-830.  abstract
  18. Fuschiotti, P., N. Harindranath, R.G. Mage, W.T. McCormack, P. Dhanarajan, & K.H. Roux.  1993.  Recombination activating genes-1 and -2 of the rabbit:  Cloning and characterization of germline and expressed genes.  Mol. Immunol. 30:1021-1032.  abstract
  19. McCormack, W.T., M. Liu, C. Postema, C.B. Thompson & L.A. Turka.  1993.  Excision products of TCR Va recombination contain in-frame rearrangements: Evidence for continued V(D)J recombination in TCR+ thymocytes.  Internatl. Immunol. 5:801-804.  abstract
  20. Pickel, J.M., W.T. McCormack, C.H. Chen, M.D. Cooper, & C.B. Thompson.  1993.  Differential regulation of V(D)J recombination during development of avian B and T cells.  Internatl. Immunol. 5:919-927.  abstract
  21. Six, A., J.P. Rast, W.T. McCormack, D. Dunon, D. Courtois, Y. Li, C.H. Chen, & M.D. Cooper.  1996.  Characterization of avian T cell receptor g genes.  Proc. Natl. Acad. Sci. USA 93:15329-15334.  abstract
  22. Sanchez-Garcia, F.J., W.W. Aller, & W.T. McCormack.  1997.  Impaired calcium mobilization and differential tyrosine phosphorylation in intestinal intraepithelial lymphocytes.  Immunology 91:81-87.  abstract
  23. Davis, J.A., E. Peen, R.C. Williams, Jr., S. Perkins, C.C. Malone, W.T. McCormack, E. Csernok, W.L. Gross, A.S. Kolaskar, & U. Kulkarni-Kale.  1998.  Determination of primary amino acid sequence and unique three dimensional structure of WGH1, a monoclonal human IgM antibody with anti-PR3 specificity. Clin. Immunol. Immunopathol. 89:35-43.  abstract
  24. Rossi, D., J. Sanchez-Garcia, W.T. McCormack, J.F. Bazan, & A. Zlotnik.  1999.  Identification of a chicken “C” chemokine related to lymphotactin.  J. Leukocyte Biol. 65:87-93.  abstract
  25. Sheng, B., W.T. McCormack, & R.T. Smith.  1999. Purified donor T cells alone activate transplantation immunity to the male antigen but induce tolerance in combination with Mac-1+ donor cells.  Transplantation 68:1024-1029.  abstract
  26. Khan, S.R., K.A. Byer, S. Thamilselvan, R.L. Hackett, W.T. McCormack, N.A. Benson, K.L. Vaughn, & G.N. Erdos.  1999.  Crystal-cell interaction and apoptosis in oxalate-associated injury of renal epithelial cells.  J. Am. Soc. Nephrology 10:S457-463.  abstract
  27. Kou, Z.C., J.S. Puhr, M. Rojas, W.T. McCormack, M.M. Goodenow, & J.W. Sleasman. 2000. T-cell receptor Vb repertoire CDR3 length diversity differs within CD45RA and CD45RO T-cell subsets in healthy and human immunodeficiency virus-infected children. Clin. Diag. Lab. Immunol. 7:953-959.  abstract
  28. Moore, J.B., R.K. Blanchard, W.T. McCormack, & R.J. Cousins. 2002. Moderate murine zinc deficiency alters specific mRNA abundances in the thymus prior to changes in CD4/CD8/CD3 T-lymphocyte populations. J. Nutrition 131:3189-3196.  abstract
  29. Casp, C.B., J.X. She, & W.T. McCormack. 2002. Genetic association of the catalase gene (CAT) with vitiligo susceptibility. Pigment Cell Res. 15:62-66.  abstract
  30. Casp, C.B., J.X. She & W.T. McCormack.  2003.  Genes of the TAP/LMP cluster are associated with the human autoimmune disease vitiligo.  Genes & Immunity 4:492-499abstract
BOOK CHAPTERS AND MONOGRAPHS
  1. McCormack, W.T. & C.B. Thompson.  1990.  Somatic diversification of the chicken immunoglobulin light chain gene.  Immunol. Rev. 48:41-67.  abstract
  2. McCormack, W.T., L.W. Tjoelker & C.B. Thompson.  1991.  Avian B cell development:  Generation of an immunoglobulin repertoire by gene conversion.  Annu. Rev. Immunol. 9:219-241.  abstract
  3. McCormack, W.T., L.W. Tjoelker & C.B. Thompson.  1993.  Immunoglobulin gene diversification by gene conversion.  Prog. Nucl. Acids Res. Mol. Biol. 45:27-45.
  4. McCormack, W.T. & C.B. Thompson.  1993.  Special features of the development of the chicken humoral immune system.  Res. Immunol. 144:467-476.
  5. Sanchez-Garcia, F.J. & W.T. McCormack.  1995.  Chicken gd T cells.  Curr. Topics Microbiol. Immunol. 212:53-67.
  6. McCormack, W.T.  1998.  Avian Immunology - T Cell Receptors.  In:  Vertebrate Immunology, Eds. P. Pastoret, H. Bazin, A. Govaertsa, P. Griebel, Academic Press Limited, London, pp. 73-136.
PUBLISHED ABSTRACTS AND SHORT REPORTS
  1. McCormack, W.T. & K.H. Roux.  1982.  Monoclonal antibodies specific for rabbit light chains bearing the b5 allotype. Fed. Proc. 41:595.
  2. McCormack, W.T. & K.H. Roux.  1984.  Analysis of the rabbit anti-a1 IdX using heterologous anti-Id antibodies.  Fed. Proc. 43:1742.
  3. Laster, S.M., W.T. McCormack, W.F. Marzluff & K.H. Roux. 1985.  Nucleotide sequence analysis and evolutionary significance of VH genes of the rabbit VHIII subgroup.  ICSU Short Reports - Adv. Gene Technol. 2:219-220.
  4. Roux, K.H., W.T. McCormack & P. Dhanarajan.  1985.  Unexpected species-specific differences in the immune response to the cross-reactive idiotype on rabbit anti-allotype antibody.  ICSU Short Reports - Adv. Gene Technol. 2:279-280.
  5. McCormack, W.T., K.H. Roux & P. Dhanarajan.  1987.  Limited polymorphism of rabbit VH genes detected with mouse VH subgroup probes.  Fed Proc. 46:489.
  6. McCormack, W.T. & K.H. Roux.  1988.  Rabbit latent VHa1 allotype sequences:  Comparison of amino acid and cDNA sequences.  J. Cell. Biochem. suppl. 12B:99.
  7. McCormack, W.T., L.M. Carlson, L.W. Tjoelker & C.B. Thompson.  1989.  Avian immunoglobulin light chain gene organization and rearrangement in the bursa.  J. Cell. Biochem. suppl. 13C:71.
  8. Tjoelker, L.W., W.T. McCormack, L.M. Carlson & C.B. Thompson.  1989.  Evolutionary comparison of the avian IgL locus.  Abstracts/7th Intl. Congress of Immunol.: Berlin (West).  Gustav Fischer Verlag, Stuttgart.  p. 13.
  9. McCormack, W.T., L.W. Tjoelker, L.M. Carlson, B. Petryniak & C.B. Thompson.  1989.  Bursal selection of the productively rearranged IgL genes during chicken development.  Abstracts / 7th Intl. Congress of Immunology: Berlin (West).  Gustav Fischer Verlag, Stuttgart.  p. 186.
  10. McCormack, W.T., L.M. Carlson, C.E. Postema, C.F. Barth, E.H. Humphries & C.B. Thompson.  1990.  Somatic hyperconversion of the chicken immunoglobulin VL gene segment in the bursa of Fabricius occurs by intrachromosomal gene conversion.  ICSU Short Reports - Adv. Gene Technol. 10:15.
  11. McCormack, W.T. & C.B. Thompson.  1990.  Generation of diversity in the chicken IgL variable region by gene conversion - A molecular model.  J. Cell. Biochem. suppl. 14D:242.
  12. Tjoelker, L.W., L.M. Carlson, W.T. McCormack & C.B. Thompson.  1990.  Cloning and characterization of the avian T cell receptor b gene locus.  FASEB J. 4:231.
  13. McCormack, W.T. & C.B. Thompson.  1991.  Meiotic gene conversion in chickens and its implications for the introduction of foreign DNA into the avian germline by homologous recombination.  J. Cell. Biochem. suppl. 15E:207.
  14. Pickel, J.M., W.T. McCormack, C.H. Chen, C.B. Thompson & M.D. Cooper.  1991.  Immunoglobulin gene rearrangement and B lineage marker expression in avian embryos.  FASEB J. 5(4): A604.
  15. Masteller, E.L., M.A. Oettinger, D.G. Schatz, L.M. Carlson, E.A. Hurley, W.T. McCormack, D. Baltimore & C.B. Thompson.  1991.  Expression of the recombination activating genes RAG-1 and RAG-2 during avian B cell development.  FASEB J. 5(5):A1380.
  16. Roux, K.H., G. Ray, & W.T. McCormack.  1993.  Expression of RAG-1 and RAG-2 mRNA in rabbit lymphoid tissue.  J. Cell. Biochem. suppl. 17B:234.
  17. Sanchez-Garcia, F.J., Six, A., Jacono, C.C., Aller, W.W., Cooper, M.D., Chen, C.H., & McCormack, W.T.  1995.  Repertoire analysis of chicken gamma/delta (TCR1) T cells.  9th Int'l Congress of Immunology.  Abstr. 1481.
  18. McCormack, W.T. & F.J. Sanchez-Garcia.  1996. Calcium mobilization and tyrosine phosphorylation in intestinal intraepithelial lymphocytes.  Abstracts - Keystone Symposia - Lymphocyte Activation, Abstr. 1071, p. 53.
  19. Aller, W., F.J. Sanchez-Garcia, & W.T. McCormack.  1996.  Calcium mobilization and tyrosine phosphorylation in avian & murine intestinal intraepithelial lymphocytes.  FASEB J. 10(6):A1448.
  20. Leung, E., L. Utley, V. Ramiya, J.R. Smyth, Jr., & W.T. McCormack.  1996.  Molecular pathogenesis of amelanosis in the Smyth line chicken, a model of human vitiligo. FASEB J. 10(6):A1316.
  21. Sanchez-Garcia, F.J., W. Aller, & W.T. McCormack.  1996.  Rescue from apoptosis in bursa B cells by soluble T cell factor(s).  FASEB J. 10(6):A1207.
  22. Kristensen, D., C.A. Bradley, M. Hao, S. Perkins, W.T. McCormack.  2000.  Case/control association study of candidate genes for vitiligo susceptibility:  tyrosine metabolism and immune response genes.  52nd Annual Meeting & Clin. Lab. Expo., Amer. Acad. Clin. Chem.
  23. Bradley, C.A., D. Kristensen, M. Hao, S. Perkins, M. Marron, J.X. She, W.T. McCormack. Case/control association study of immune response genes and vitiligo susceptibility.  2000. Amer. Assoc. Immunol.
  24. Bradley, C.A., D. Kristensen, J.X. She, W.T. McCormack. 2001. Genetic association studies of immune response genes and vitiligo susceptibility. FASEB J. 15(4):A323.
  25. McCormack, W.T., Bradley, C.A., D. Kristensen, J.X. She. 2001. Genetics of vitiligo susceptibility: Association studies of immune response genes. Pigment Cell Res. 14(3):231.
  26. Casp, C.B., S.A. Litherland, J.-X. She, W.T. McCormack. 2002. Antigen processing and presentation genes in vitiligo suceptibility. FASEB J. 16(5):A1219.

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         Last updated:  4/1/04