Li Yin, MD, PhD
Assistant Professor
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Dept. of Pathology, Immunology and Laboratory Medicine |
Primary Areas of Research:
- Applying revolutionary massive parallel pyrosequencing technology to investigate:
- Characteristics, diversity and correlation of human immunoglobulin in healthy adolescents.
- Immunoglobulin profiling in healthy and diseases including adolescents with autoimmune diseases and/or HIV-infection.
- Breadth and depth of HIV-1 quasispecies within infected individuals and population dynamics over time and after antiretroviral therapy.
- Prevalence of HPV genotypes in a multinational cohort of HPV-infected men.
- Applying spectratyping technology to study the genetic length polymorphism in HIV-1 Env variable domains and its correlation with disease progression and response to antiretroviral therapy.
- Dynamics of T cell activation over the course of infection and after antiretroviral therapy in pediatric patients who demonstrated different responses to treatment.