Publications

Peer Reviewed Papers

Primary human hepatocyte culture for HCV study.

Zhu H, Elyar J, Foss R, Hemming A, Hall E, Lecluyse EL, Liu C.

Methods Mol Biol. 2009;510:373-82.

PMID: 19009276 [PubMed - in process]

The utility of p16(Ink4a) in discriminating between cervical intraepithelial neoplasia 1 and nonneoplastic equivocal lesions of the cervix.

Redman R, Rufforny I, Liu C, Wilkinson EJ, Massoll NA.

Arch Pathol Lab Med. 2008 May;132(5):795-9.

PMID: 18466028 [PubMed - indexed for MEDLINE]

Water-soluble nanocrystals through dual-interaction ligands.

Wu H, Zhu H, Zhuang J, Yang S, Liu C, Cao YC.

Angew Chem Int Ed Engl. 2008;47(20):3730-4. No abstract available.

PMID: 18399517 [PubMed - indexed for MEDLINE]

Identification of liver cancer-specific aptamers using whole live cells.

Shangguan D, Meng L, Cao ZC, Xiao Z, Fang X, Li Y, Cardona D, Witek RP, Liu C, Tan W.

Anal Chem. 2008 Feb 1;80(3):721-8. Epub 2008 Jan 5.

PMID: 18177018 [PubMed - indexed for MEDLINE]

The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1.

Butler SL, Dong H, Cardona D, Jia M, Zheng R, Zhu H, Crawford JM, Liu C.

Lab Invest. 2008 Jan;88(1):78-88. Epub 2007 Nov 19.

PMID: 18026163 [PubMed - indexed for MEDLINE]

Hepatitis C virus triggers apoptosis of a newly developed hepatoma cell line through antiviral defense system.

Zhu H, Dong H, Eksioglu E, Hemming A, Cao M, Crawford JM, Nelson DR, Liu C.

Gastroenterology. 2007 Nov;133(5):1649-59. Epub 2007 Sep 16.

PMID: 17983809 [PubMed - indexed for MEDLINE]

Primary presacral neuroendocrine tumor associated with imperforate anus.

Kim T, Grobmyer SR, Liu C, Hochwald SN.

World J Surg Oncol. 2007 Oct 11;5:115.

PMID: 17931412 [PubMed - in process]

Anti-hepatitis C virus activity of albinterferon alfa-2b in cell culture.

Liu C, Zhu H, Subramanian GM, Moore PA, Xu Y, Nelson DR.

Hepatol Res. 2007 Nov;37(11):941-7. Epub 2007 Jun 15.

PMID: 17573950 [PubMed - in process]

Hepatocellular carcinoma cell supernatants increase expansion and function of CD4(+)CD25(+) regulatory T cells.

Cao M, Cabrera R, Xu Y, Firpi R, Zhu H, Liu C, Nelson DR.

Lab Invest. 2007 Jun;87(6):582-90. Epub 2007 Mar 19.

PMID: 17372588 [PubMed - indexed for MEDLINE]

Hepatocellular carcinoma arising from ectopic liver tissue in the pancreas.

Cardona D, Grobmyer S, Crawford JM, Liu C.

Virchows Arch. 2007 Feb;450(2):225-9.

PMID: 17216188 [PubMed - indexed for MEDLINE]

Hepatitis C virus: virology and experimental systems.

Liu C.

Clin Liver Dis. 2006 Nov;10(4):773-91. Review.

PMID: 17164117 [PubMed - indexed for MEDLINE]

Betaine resolves severe alcohol-induced hepatitis and steatosis following liver transplantation.

Samara K, Liu C, Soldevila-Pico C, Nelson DR, Abdelmalek MF.

Dig Dis Sci. 2006 Jul;51(7):1226-9. No abstract available.

PMID: 16944015 [PubMed - indexed for MEDLINE]

Presentation and management of gastrointestinal stromal tumors of the duodenum.

Winfield RD, Hochwald SN, Vogel SB, Hemming AW, Liu C, Cance WG, Grobmyer SR.

Am Surg. 2006 Aug;72(8):719-22; discussion 722-3.

PMID: 16913316 [PubMed - indexed for MEDLINE]

Familial aggregation of insulin resistance in first-degree relatives of patients with nonalcoholic fatty liver disease.

Abdelmalek MF, Liu C, Shuster J, Nelson DR, Asal NR.

Clin Gastroenterol Hepatol. 2006 Sep;4(9):1162-9. Epub 2006 Aug 8.

PMID: 16901766 [PubMed - indexed for MEDLINE]

Combined hepatic resection and radiofrequency ablation for multiple hepatic adenomas.

Fujita S, Kushihata F, Herrmann GE, Mergo PJ, Liu C, Nelson D, Fujikawa T, Hemming AW.

J Gastroenterol Hepatol. 2006 Aug;21(8):1351-4.

PMID: 16872326 [PubMed - indexed for MEDLINE]

An effective cancer vaccine modality: lentiviral modification of dendritic cells expressing multiple cancer-specific antigens.

Wang B, He J, Liu C, Chang LJ.

Vaccine. 2006 Apr 24;24(17):3477-89. Epub 2006 Feb 28.

PMID: 16530303 [PubMed - indexed for MEDLINE]

Cyclosporine suppresses hepatitis C virus in vitro and increases the chance of a sustained virological response after liver transplantation.

Firpi RJ, Zhu H, Morelli G, Abdelmalek MF, Soldevila-Pico C, Machicao VI, Cabrera R, Reed AI, Liu C, Nelson DR.

Liver Transpl. 2006 Jan;12(1):51-7.

PMID: 16382464 [PubMed - indexed for MEDLINE]

Defective Jak-Stat activation in hepatoma cells is associated with hepatitis C viral IFN-alpha resistance.

Zhu H, Nelson DR, Crawford JM, Liu C.

J Interferon Cytokine Res. 2005 Sep;25(9):528-39.

PMID: 16181053 [PubMed - indexed for MEDLINE]

Novel type I interferon IL-28A suppresses hepatitis C viral RNA replication.

Zhu H, Butera M, Nelson DR, Liu C.

Virol J. 2005 Sep 7;2:80.

PMID: 16146571 [PubMed]

Breast implants as a possible etiology of epithelioid hemangioendothelioma and successful therapy with interferon-alpha2.

Marsh Rde W, Walker MH, Jacob G, Liu C.

Breast J. 2005 Jul-Aug;11(4):257-61.

PMID: 15982392 [PubMed - indexed for MEDLINE]

Human papillomavirus infection and p16(INK4a) protein expression in vulvar intraepithelial neoplasia and invasive squamous cell carcinoma.

Rufforny I, Wilkinson EJ, Liu C, Zhu H, Buteral M, Massoll NA.

J Low Genit Tract Dis. 2005 Apr;9(2):108-13.

PMID: 15870532 [PubMed - indexed for MEDLINE]

Impact of humoral immune response on distribution and efficacy of recombinant adeno-associated virus-derived acid alpha-glucosidase in a model of glycogen storage disease type II.

Cresawn KO, Fraites TJ, Wasserfall C, Atkinson M, Lewis M, Porvasnik S, Liu C, Mah C, Byrne BJ.

Hum Gene Ther. 2005 Jan;16(1):68-80.

PMID: 15703490 [PubMed - indexed for MEDLINE]

Cytokeratin 20 confirms merkel cell metastasis to stomach.

Li M, Liu C.

Appl Immunohistochem Mol Morphol. 2004 Dec;12(4):346-9.

PMID: 15536335 [PubMed - indexed for MEDLINE]

An immunomodulatory role for CD4(+)CD25(+) regulatory T lymphocytes in hepatitis C virus infection.

Cabrera R, Tu Z, Xu Y, Firpi RJ, Rosen HR, Liu C, Nelson DR.

Hepatology. 2004 Nov;40(5):1062-71.

PMID: 15486925 [PubMed - indexed for MEDLINE]

STAT3 induces anti-hepatitis C viral activity in liver cells.

Zhu H, Shang X, Terada N, Liu C.

Biochem Biophys Res Commun. 2004 Nov 12;324(2):518-28.

PMID: 15474458 [PubMed - indexed for MEDLINE]

One-year protocol liver biopsy can stratify fibrosis progression in liver transplant recipients with recurrent hepatitis C infection.

Firpi RJ, Abdelmalek MF, Soldevila-Pico C, Cabrera R, Shuster JJ, Theriaque D, Reed AI, Hemming AW, Liu C, Crawford JM, Nelson DR.

Liver Transpl. 2004 Oct;10(10):1240-7.

PMID: 15376304 [PubMed - indexed for MEDLINE]

FAP with concurrent duodenal adenomatous polyposis and carcinoid tumor.

Camp ER, Hochwald SN, Liu C.

J Surg Oncol. 2004 Sep 15;87(4):187-90.

PMID: 15334634 [PubMed - indexed for MEDLINE]

Stabilized beta-catenin promotes hepatocyte proliferation and inhibits TNFalpha-induced apoptosis.

Shang XZ, Zhu H, Lin K, Tu Z, Chen J, Nelson DR, Liu C.

Lab Invest. 2004 Mar;84(3):332-41.

PMID: 14767485 [PubMed - indexed for MEDLINE]

Sustained viral response to interferon and ribavirin in liver transplant recipients with recurrent hepatitis C.

Abdelmalek MF, Firpi RJ, Soldevila-Pico C, Reed AI, Hemming AW, Liu C, Crawford JM, Davis GL, Nelson DR.

Liver Transpl. 2004 Feb;10(2):199-207.

PMID: 14762857 [PubMed - indexed for MEDLINE]

beta-Catenin is expressed aberrantly in tumors expressing shadow cells. Pilomatricoma, craniopharyngioma, and calcifying odontogenic cyst.

Hassanein AM, Glanz SM, Kessler HP, Eskin TA, Liu C.

Am J Clin Pathol. 2003 Nov;120(5):732-6.

PMID: 14608900 [PubMed - indexed for MEDLINE]

Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect.

Nelson DR, Tu Z, Soldevila-Pico C, Abdelmalek M, Zhu H, Xu YL, Cabrera R, Liu C, Davis GL.

Hepatology. 2003 Oct;38(4):859-68.

PMID: 14512873 [PubMed - indexed for MEDLINE]

CD8+ T-cell interaction with HCV replicon cells: evidence for both cytokine- and cell-mediated antiviral activity.

Liu C, Zhu H, Tu Z, Xu YL, Nelson DR.

Hepatology. 2003 Jun;37(6):1335-42.

PMID: 12774012 [PubMed - indexed for MEDLINE]

Gene expression associated with interferon alfa antiviral activity in an HCV replicon cell line.

Zhu H, Zhao H, Collins CD, Eckenrode SE, Run Q, McIndoe RA, Crawford JM, Nelson DR, She JX, Liu C.

Hepatology. 2003 May;37(5):1180-8.

PMID: 12717400 [PubMed - indexed for MEDLINE]

Interleukin-1 inhibits hepatitis C virus subgenomic RNA replication by activation of extracellular regulated kinase pathway.

Zhu H, Liu C.

J Virol. 2003 May;77(9):5493-8.

PMID: 12692250 [PubMed - indexed for MEDLINE]

Combination of interferon alfa-2b and ribavirin in liver transplant recipients with histological recurrent hepatitis C.

Firpi RJ, Abdelmalek MF, Soldevila-Pico C, Reed A, Hemming A, Howard R, Van Der Werf W, Lauwers G, Liu C, Crawford JM, Davis GL, Nelson DR.

Liver Transpl. 2002 Nov;8(11):1000-6.

PMID: 12424712 [PubMed - indexed for MEDLINE]

Abstracts Presented at meetings

1. Eksioglu, E. A., Bayouth, L.A., Bess, J.R., Zhu, H., Zhang, X., Garraway, K., Nelson, D.R., Liu, C. Role of RIG-I in the Induction of Type I IFN by Hepatitis C Virus. Abstract accepted for poster presentation, 15th International Symposium on Hepatitis C Virus and Related Viruses. San Antonio, TX. October 2008.

2. Bess, J.R., Eksioglu, E. A., Dong, HJ., Chan, E., Nelson, D.R., Liu, C. Autoantibodies and neutralizing antibodies in human patients with chronic hepatitis C viral infection. Abstract accepted for poster presentation, 15th International Symposium on Hepatitis C Virus and Related Viruses. San Antonio, TX. October 2008.

3. Zhu, H., Eksioglu, E. A., Bess, J.R., Nelson, D.R., Liu, C. Innate Immune Response in HCV-infected Primary Human Hepatocytes. Abstract accepted for poster presentation, 15th International Symposium on Hepatitis C Virus and Related Viruses. San Antonio, TX. October 2008.

4. Eksioglu, E. A., Bess, J.,Dangmeon, P., Zhu, H., Firpi, R., Nelson, D.R., Liu, C. Role of IL-10 Therapy in the Neutralizing Antibody Activity of Chronic HCV Patients. Abstract accepted for poster presentation, Keystone Symposia, Cell Biology of Virus Entry Replication and Pathogenesis. Victoria, BC, Canada. April 2008.

5. Bess, J., Eksioglu, E A., Dong, HJ., Jones, G., Liu, C. Characterization of neutralizing antibodies and auto-antibodies in chronic hepatitis C viral infection. Abstract accepted for poster presentation, Keystone Symposia, Cell Biology of Virus Entry Replication and Pathogenesis. Victoria, BC, Canada. April 2008.

6. Liu, C; Coco, D; Dong, HJ; Eksioglu, E; Zhu, H; Ostrov, D. Novel Antiviral Small Molecules that Blocks Hepatitis C Virus Cellular Entry Through the CD81 Receptor. 14th International Symposium on Hepatitis C Virus and Related Viruses. Glasgow, Scotland, UK. September 2007.

7. Zhu, H; Dong, HJ; Eksioglu, E; Hemming, A; Cao, M; Crawford, JM; Nelson, DR; Liu, C. Hepatitis C Virus Induces Liver Cell Apoptosis through Activation of Innate Antiviral Defense System. Hepatitis Single Topic Conference AASLD. Interferon and Ribavirin in Hepatitis C Virus Infection: Mechanisms of Response and Non-Response. Chicago, IL. March 2007.

8. Eksioglu, E. A., Zhu, H., Xu, Y., Bess, J., Nelson, D.R., Liu, C. Dendritic cell responses to hepatitis C virus. Abstract accepted for poster presentation, Keystone Symposia, Immunological Intervention in Human Disease. Big Sky, MT. January 2007. Travel Scholarship award. Selected for oral presentation.

9. Bess, J., Elyar, J., Dong, H., Eksioglu, E. A., Witek, R., Zhu, H., Liu, C. Neutralizing Antibody in HCV Infection. Abstract accepted for poster presentation, Keystone Symposia, Immunological Intervention in Human Disease. Big Sky, MT. January 2007. Travel Scholarship award.

Welcome to the Liu Lab Webpage

Chen Liu MD/PhD P.I

Publications