Marguerite Hatch B.Sc., Ph.D.
Associate Professor

Dept. of Pathology, Immunology and Laboratory Medicine
University of Florida College of Medicine
P.O. Box 100275
Gainesville, FL 32610-0275

Office Location and Express Mail address:

1600 SW Archer Rd.
Room D6-33A
Gainesville FL 32610

Office: (352) 392-0013
Fax: : (352) 392-3053
Email: hatchma@ufl.edu

Primary Area of Research:
Research in my laboratory is presently directed towards elucidating epithelial tranport mechanisms for extra-renal excretion of electrolytes such as potassium and the organic anions oxalate and urate. In addition, I have had a long-time interest in the pathophysiology of kidney stone disease and renal excretion of oxalate. We have made significant contributions regarding the transport mechanisms involved in oxalate transport across various segments of the intestinal tract by identifying and characterizing both absorptive and secretory pathways involved in regulating mass balance of oxalate. We have recently demonstrated that extra-renal excretion of both oxalate and urate can occur via the large intestine and we have shown that this enteric excretory route plays an important role when renal function is compromised. This physiological adaptation involves alterations in epithelial cell membrane transport processes and appears to be partly mediated by a local up-regulation in angiotensin II receptors. The extracellular and intracellular mediators involved in the signaling transduction process initiating these alterations in electrolyte and organic anion transport is a current focus.

Marguerite Hatch B.Sc., Ph.D. Associate Professor

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Marguerite Hatch B.Sc., Ph.D.
Associate Professor