Renal Pathology


The renal biopsy technique has greatly enhanced our understanding of the pathology, pathogenic mechanisms, and classification of renal diseases. It represents a valuable procedure to diagnose renal disease, assess the prognosis, aid in the selection of a specific therapeutic approach, and monitor disease progression. The technique is useful in the evaluation of diseases that affect both native and allograft kidneys.

To obtain the maximum amount of information from a renal biopsy specimen, a combination of light, immunofluorescence, and electron microscopy are utilized. Since these different forms of microscopy require different methods of fixation and processing, the renal biopsy core fragment is usually divided into three parts. However, depending on the length of the biopsy core or the suspected disease process, the method of dividing the biopsy core may be modified.

Sample Reports: Renal

Test List

Renal Pathology, General Info.  (Byron P. Croker, M.D., Ph.D.; William L. Clapp, M.D.)

  Test Order Number:
  Methodology:Light microscopy, electron microscopy, immunofluorescence (direct and indirect), special stains (conventional and immunohistochemistry).
  Specimen Requirements:Tissue in buffered formalin or other appropriate fixative for light microscopy and electron microscopy; Michel's media for immunofluorescence; pre-prepared slides; paraffin blocks.
  Specimen Handling:
  In-house turnaround time:4 to 10 days
  Reference Values:Interpretive report
  CPT Code:

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