Ying Li, MD, PhD
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Dept. of Pathology,
Immunology and Laboratory Medicine University of Florida College of Medicine P.O. Box 100275 Gainesville, FL 32610-0275 Office Location and Express Mail address: Office: (352) 265-0111 x72052 |
Currently Involved In:My research interest is to use flow cytometric analysis to identify potential low-grade stem cell disorders. Hematopathologic diagnosis of the low-grade stem cell disorders (myelodysplastic syndrome and/or myeloproliferative disorders) is still a challenging process in clinical practice in that the diagnosis is based clinical history and certain morphologic features, which is non-specific and may not present in many of the stem cell disorders. Although results of cytogenetics studies become the diagnostic gold standard in clinical practice, there is no specific genetic defects yet discovered for majority of the low-grade stem cell disorders. Because these diseases are clonal processes of the stem cells, clonal-related surface antigen alternations may be observed on these abnormal cells by flow cytometric analysis. We are using flow cytometric analysis to study the developmental-related expression of myeloid, erythroid and megakaryocytic markers on immature marrow precursor cells during their maturation so that we are able to differentiate the abnormal maturational processes (in stem cell disorders) from their normal counterparts.
Curriculum Vitae (click to download MS-Word document)
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