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Publications:

Selected Peer-Reviewed Publications (in reverse order)

Haoyang Zhuang, Matthew Kosboth, Jennifer A. Sipos, Minoru Satoh, Lijun Yang, and Westley H. Reeves. Chapter 6. Autoimmunity  In press

 

Koya V, Lu S, Sun YP, Purich DL, Atkinson MA, Li SW, Yang LJ.  Reversal of streptozotocin-induced diabetes in mice by cellular transduction with recombinant pancreatic transcription factor pancreatic duodenal homeobox-1: a novel protein transduction domain-based therapy.  Diabetes. 2008 Mar;57(3):757-69. Epub 2007 Dec 17

 

Yang F, Li Y, Braylan R, Hunger SP, Yang LJ. Pediatric T-cell post-transplant lymphoproliferative disorder after solid organ transplantation.  Pediatr Blood Cancer. 2008 Feb;50(2):415-8.

 

Han S, Wang B, Cotter MJ, Yang LJ, Zucali J, Moreb JS, Chang LJ. Overcoming immune tolerance against multiple myeloma with lentiviral calnexin-engineered dendritic cells. Mol Ther. 2008 Feb;16(2):269-79. Epub 2007 Dec 11.

 

Al-Quran SZ, Yang LJ, Magill JM, Braylan RC, Douglas-Nikitin VK. Assessment of bone marrow plasma cell infiltrates in multiple myeloma: the added value of CD138 immunohistochemistry.  Hum Pathol. 2007 Dec;38(12):1779-87. Epub 2007 Aug 2

Yang, L.J. (2006). Liver Stem Cells Derived Surrogates for Treatment of Type 1 Diabetes. Autoimmunity Reviews. July;5(6):409-413

Tang, D.Q., Cao, L.Z., Li, S.W., Farag, C., Chang, L.J. & Yang, L.J. (2006). Role of Pax4 in Pdx1-VP16 mediated liver-to-endocrine pancreas transdifferentiation. Laboratory Investigation. Aug;86(8):829-41

Tang DQ, Lu S, Sun YP, Rodriguez E, Chou W, Yang C, Cao LZ, Chang L.J, & Yang, L.J.(2006). Reprogramming liver-stem WB cells into functional insulin-producing cells by persistent expression of Pdx1- and Pdx1-VP16 mediated by lentiviral vectors. Laboratory Investigation. Jan;86(1):83-93

Xiong, C, Xie C.Q., Zhang, L, Zhang, J., Xu, K., Fu, M., Thompson, WE, Yang, L.J., & Chen, YE. (2005). Derivation of adipocytes from human embryonic stem cells. Stem Cell and Development. Dec;14(6):671-675

Chen, X, Tang, D.Q., Xie, C.Q., Thompson, W.E., Chang, L.J, Chen, Y.E, & Yang, L.J. (2005) .Genetic Engineering of Human Embryonic Stem Cells with Lentiviral Vectors. Stem Cell and Development. Aug; 14:367-377

Peck, A.B., Petersen, B., Ramiya, V. & Yang, L.J. (2005). The many faces of adult stem cellderived, in vitro-generated insulin-producing islet-like cells for the treatment of type 1 diabetes. In: Progress in Stem Cell Research Ed: Markino M. Nova Science Publishers, Inc., New York

Cao, L.Z., Tang, D.Q., Li, S.W., Horb, M.A. and Yang, L.J. (2004). External factors are necessary for Pdx-1 transfected hepatic cells to transdifferentiate into functional pancreatic endocrine insulin-producing cells. Diabetes. 53(12):3168-3178

Tang, D.Q., Cao, L.Z., Burkhardt, B.R., Xia, C.Q., Litherland, S.A., Atkinson, M.A., and Yang, L.J. (2004) In vivo and in vitro characterization of insulin-producing cells obtained from murine bone marrow. Diabetes. 53(7):1721-32

Yuan, C., Douglas, V., Luchetta, G., Ahrens, K., Braylan, R. and Yang, L.J. (2004). Drag5-based cell cycle analysis of cell subpopulations discriminated by surface antigens and light scatter in hematopoietic tissue. Flow Cytometry, 58B:47-52

Li, S.W., Tang, D.Q., Ahrens, KP, She, J.X., Braylan, R.C., Yang, L.J. (2003) All-trans-retinoic acid induces CD52 expression in acute promyelocytic leukemia. Blood. 101(5):1977-80.

Yang, L.J., Zhao, H.S., Li, S.W., Collins, and. She, J.X. (2003). Gene expression patterns of retinoid acid-induced granulocytic differentiation of acute promyelocytic leukemic cells. J. Molecular Diagnostics. 5(4):212-221

Yang, L.J., Li, S.W., Hatch, H., Ahrens, K., Petersen, B.E. & Peck, A.B. (2002). In vitro transdifferentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells. Proc Natl Acad Sci U S A. 99: 8078-8083

Maloney, J.A., Tsygankova, O.M., Yang, L.J., Li, Q.Y., Szot, A., Baysal, K., and Williamson, J.R. (1999). Activation of ERK by Ca2+ store depletion in rat liver epithelial cells. Am J Physiol (Cell Physiol ) 276: C221-C230

Yang, L.J., Guo, Y.L., Maloney, J. A., & Williamson, L.R. (1999). Angiotensin II Regulation of Extracellular Signal-regulated Protein Kinase in Rat Liver Epithelial WB cells. Biochemical Pharmacology, 57: 425-432

Guo, Y.L., Kang, B., Yang, L.J. and Williamson, J. R. (1999) Tumor necrosis factor- alpha and ceramide induce cell death through different mechanisms in rat mesangial cells. Am. J. Physiology, 276 (Renal Physiol.) 45: F390-F397

Guo, Y.L., Baysal,K., Kang, B., Yang, L.J., and Williamson, J.R. (1998) Correlation between Sustained c-Jun N-terminal Protein Kinase Activation and Apoptosis Induced by Tumor Necrosis Factor-alpha in Rat Mesangial Cells. J. Biol. Chem., 273: 4027-4034

Maloney, J.A., Tsygankova, O., Szot, A., Yang, L.J., Li, Q.Y., Williamson, J. R. (1998)Differential translocation of protein kinase C isozymes by phorbol esters, EGF, and ANG II in rat liver WB cells. Am J Physiol (Cell Physiol) 274: C974-C982

Pei, Z.D., Maloney, J.A., Yang, L.J., and Williamson, J.R. (1997). A new function for phospholipase C-γ1: Coupling to the adaptor protein GRB2. Arch. Biol. & Biophys., 345:103-110

Pei, Z. D., Yang, L. J., and Williamson, J. R. (1996) Phospholipase C-γ1 binds to actincytoskeleton via its C-terminal SH2 domain in vitro. Biochem. Biophys. Res. Commu., 228: 802-806

Yang, L.J., Rhee, S.G. and Williamson, J. R. (1994). Epidermal growth factor- induced activation and translocation of phospholipase C--γ to the cytoskeleton in rat hepatocytes. J. Biol. Chem., 269: 7156-7162

Baffy, G., Yang, L.J., Raj, S., Manning, D.R. and Williamson, J. R. (1994) G-protein coupling to the thrombin receptors in Chinese hamster lung fibroblasts. J. Biol. Chem., 269:8483-8487

Baffy, G., Yang, L.J., Wolf, B.A., and Williamson, J. R. (1993) G-protein specificity in signaling pathways that mobilize calcium in the insulin-secreting - TC3 cells. Diabetes. 42: 1878-1882 PMID: 8243834

Yang, L.J., Camoratto, A.M, Baffy, G., Raj, S., Manning, D.R. and Williamson, J.R. (1993) Epidermal growth factor-mediated signaling of Gi-protein to activation of phospholipases in cultured rat hepatocytes. J. Biol. Chem. 268: 3739-3746

Baffy,G., Yang, L.J., Michalopoulos, G.K. and Williamson, J.R. (1992) Hepatocyte growth factor induces calcium mobilization and inositol phosphate production in rat hepatocyes. J. Cell Physio. 153: 332-339 PMID: 1429853

Hansen,C.A., Yang, L.J. and Williamson, J.R. (1991) Mechanisms of receptor- mediated Ca2+ signaling in rat hepatocytes. J. Biol. Chem. 266:18573-18579

Yang, L.J., Baffy,G., Rhee,S.G., Manning, D., Hansen, C.A. and Williamson, J.R. (1991 Pertussis toxin-sensitive Gi-protein involvement in epidermal growth factor-induced activation of phospholipase C-r in rat hepatocytes. J. Biol. Chem. 266:22451-2245